In immunotherapy, T-cell is often the main subject as it plays a central role in the immune response. The PD-1 on T-cell is a protein known as an inhibitory receptor. Though the structure of glycosylated PD-1 is recognized, it’s functional significance, especially on the regulatory mechanism of T-cell activation was largely unknown. This study had established a better characteristic and mechanistic understanding of the interaction between T-cells and tumor cells.
Read More2021.11.19
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