SPEAKERS
Hideyuki Saya
AFFILIATION:
Fujita Health University, Aichi, Japan
POSITION TITLE:
Director and Professor, Fujita Cancer Center
Emeritus Professor, Keio University, Tokyo, Japan
EDUCATION/TRAINING:
Kobe University School of Medicine, Kobe, Japan, Ph.D., 1987, Immunology
Kobe University School of Medicine, Kobe, Japan, M.D., 1981, Medicine
Post-Doc, Brain Tumor Research Center, University of California, San Francisco, Jan. 1987-Jun 1988
HONORS:
The 6th Special Research Award, Sagawa Foundation for Promotion of Cancer Research, 2008
The 29th Yoshida Prize, Japanese Cancer Association, 2020
Fukuzawa Prize, Keio University, 2020
RESEARCH INTERESTS:
Active
Project for Elucidating and Controlling Mechanisms of Aging and Longevity, Japan Agency for Medical Research and Development (AMED)
Co-investigator
“Elucidation of mechanisms regulating aging of intestinal tract by stromal cells”, 10/01/2017-03/31/2022, 10,000,000 yen/yr (approximately $100,000/yr), 10% effort
Grant-in-Aid for Scientific Research (A) from the Ministry of Education, Culture, Sports, Science and Technology, Japan Cancer Research Grant from the Ministry of Education, Science and Culture of Japan
Principle Investigator
“Elucidation of induction mechanism of cancer-associated fibroblasts by MKL1 transcriptional regulator and its clinical applications”, 04/01/2017-03/31/2023, 14,000,000 yen/yr (approximately $140,000/yr), 10% effort
Practical Research for Innovative Cancer Control, Japan Agency for Medical Research and Development (AMED)
Principle Investigator
“Development of cancer stem cell targeting therapy by using polyethylene glycol-conjugated sulfasalazine (PEG-SSZ) based on DDS technology”, 04/01/2017-03/31/2020, 36,250,000 yen/yr (approximately $360,000/yr), 10% effort
Completed (2007-2020)
Practical Research for Innovative Cancer Control, Japan Agency for Medical Research and Development (AMED)
Principle Investigator
“Development of cancer stem cell targeting therapy by using polyethylene glycol-conjugated sulfasalazine (PEG-SSZ) based on DDS technology”, 04/01/2017-03/31/2020, 36,250,000 yen/yr (approximately $360,000/yr), 10% effort
Grant-in-Aid for Scientific Research (A) from the Ministry of Education, Culture, Sports, Science and Technology, Japan Cancer Research Grant from the Ministry of Education, Science and Culture of Japan
Principle Investigator
“Development of new therapeutic strategies to suppress invasiveness of glioblastoma by targeting the invasive complex composed by glioma stem cells and endothelial cells”, 04/01/2013-03/31/2016, 12,000,000 yen/yr (approximately $120,000/yr), 10% effort
Next-generation Cancer Research Strategy Promotion Project, The Ministry of Education, Culture, Sports, Science and Technology, Japan
Principle Investigator
“Development of drugs inducing transdifferentiation by regulating transcription factors based on actin dynamics”, 10/01/2014-03/31/2016, 20,000,000 yen/yr (approximately $210,000/yr), 20% effort
Translational Research Network Program, The Ministry of Education, Culture, Sports, Science and Technology, Japan
Principle Investigator
“Phase I investigator-initiated clinical trial evaluating first-line treatment with sulfasalazine plus pemetrexed and cisplatin, which targets cancer stem cells in progressive non-squamous non-small cell lung cancers”, 04/01/2014-03/31/2017, 30,000,000 yen/yr (approximately $320,000/yr), 20% effort
Grant-in-Aid for Scientific Research on Innovative Areas "Cancer Stem Cells" of The Ministry of Education, Culture, Sports, Science, and Technology, Japan.
Principle Investigator
“Development of strategies for drug resistance of cancer stem cells”, 04/01/2010-03/31/2015, 31,000,000 yen/yr (approximately $330,000/yr), 20% effort
Grant-in-Aid for Scientific Research (A) from the Ministry of Education, Culture, Sports, Science and Technology, Japan Cancer Research Grant from the Ministry of Education, Science and Culture of Japan
Principle Investigator
“Development of new therapeutic strategies to overcome drug resistance and invasiveness of glioblastoma by using mouse brain tumor models based on cancer stem cells”, 04/01/2010-03/31/2013, 15,900,000 yen/yr (approximately $160,000/yr), 10% effort
Grant from Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency (JST)
Principle Investigator
“Analysis of abnormal regulation of cell differentiation and drug development research by using induced cancer stem cells”, 06/01/2008-03/31/2014, 70,000,000 yen/yr (approximately $730,000/yr), 60% effort
Grant for Cancer Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan Cancer Research Grant from the Ministry of Education, Science and Culture of Japan Principle Investigator
“Screening of inhibitors for cancer invasion and metastasis by using the EMT visualizing system”, 04/01/2010-03/31/2011, 3,100,000 yen/yr (approximately $32,000/yr), 5% effort
Grant for Cancer Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan Cancer Research Grant from the Ministry of Education, Science and Culture of Japan Principle Investigator
“Impairment of mitotic regulation and its role in carcinogenesis”, 04/01/2005-03/31/2010, 25,000,000 yen/yr (approximately $220,000/yr), 20% effort
Grant for Cancer Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan Cancer Research Grant from the Ministry of Education, Science and Culture of Japan Principle Investigator
“Development of new molecular therapeutic approaches for malignant brain tumors”, 04/01/2007-03/31/2009, 20,000,000 yen/yr (approximately $180,000/yr), 15% effort
Grant from Program for Promotion of Fundamental Studies in Health Sciences of the National Institute of Biomedical Innovation (NiBio), Japan Co-Investigator
“Development of drugs for cancer invasion and metastasis”, 04/01/2007-03/31/2010, 16,000,000 yen/yr (approximately $160,000/yr), 5% effort
PUBLICATIONS:
https://www.scopus.com/authid/detail.uri?authorId=7007113088