Programme

SPEAKERS

Dinshaw J. Patel

AFFILIATION:

Memorial Sloan-Kettering Cancer Center (MSKCC), New York, NY, USA

POSITION TITLE:

Member and Abby Rockefeller Mauze Chair in Experimental Therapeutics

EDUCATION/TRAINING:

University of Mumbai, Mumbai, India.                                       B.S.    1961        Chemistry
California Institute of Technology, Pasadena, CA.                M.S.    1963        Chemistry
New York University, New York, NY.                                          Ph.D.    1968        Chemistry
New York Univ. Medical School New York, NY.                Postdoc    1967        Biochemistry
AT&T Bell Laboratories, Murray Hill, NJ.                          Postdoc      1968-9     Biophysics

 

HONORS:

1961 - 1963     Jamshetjee N. Tata Fellow
1983                AT&T Bell Laboratories Distinguished Technical Staff Award
1992 -              Abby Rockefeller Mauzé Chair in Experimental Therapeutics (MSKCC)
1997                Distinguished Alumnus Award, New York University
1997 - 1999     Harvey Society (Vice-President 97-98; President 98-99)
2009                Member, National Academy of Science, USA
2013                NIH Director's Transformative R01 Award (with Thomas Tuschl and Uwe Ohler)
2014                2014 FEZANA Jamshed and Shirin Guzdar Excellence in Profession Award
2015                Einstein Professorship of Chinese Academy of Sciences, China
2019                Lifetime Achievement Award, American Association of Indian Scientists in Cancer Research
2019                Inaugural Tan Jiazhen International Life Science Collaboration Award

 

 

RESEARCH INTERESTS:

Dr. Patel’s laboratory began to increasingly use x-ray crystallography starting around 2000 with the emphasis initially on RNA-mediated gene regulation, with subsequent extension to histone-mark and DNA-mark mediated epigenetic regulation, to lipid transfer proteins, and more recently to nucleic acid pattern recognition receptors and CRISPR-Cas surveillance complexes. We have complemented our structural efforts with functional studies undertaken by collaborators to deduce mechanistic insights into the biological systems of interest. Starting in 2019, my group has increasingly used cryoEM to study macromolecular structure, recognition and regulation.

 

PUBLICATIONS:

List of published work in Google Scholar:
https://scholar.google.com/citations?hl=en&user=OSxYKeQAAAAJ